Publications Digest

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Sustainability Publications Digest. In a recent publication, Garin et al. developed a framework to promote sustainable inhaler prescriptions in Spain. The authors created a national database and decision-making algorithm to integrate environmental impact into clinical decision-making processes. Their analysis found that targeted shifts from high-emission pressurized metered-dose inhalers to dry powder inhalers could yield substantial environmental benefits. The study offers actionable insights for aligning respiratory treatment practice with environmental sustainability.

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Publications Digest. In a recent publication, Weimar et al. developed a taxonomy and identified six archetypes of business models used by digital health technologies (DHTs) in the European Union. Drawing from 169 real-world DHT cases and 13 expert interviews, the study categorized models as: (1) administration and communication supporter, (2) insurer-to-consumer digital therapeutics and care, (3) diagnostic and treatment enabler, (4) professional monitoring platforms, (5) clinical research and solution accelerators, and (6) direct-to-consumer wellness and lifestyle. The authors identified three key innovation drivers in the DHT commercialization landscape: the direct targeting of patients and private individuals, the use of artificial intelligence as an enabler, and the development of DHT-specific reimbursement pathways.

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its EU HTA Publications Digest. In a recent publication, Julian et al. investigated how EU stakeholders perceive key challenges in implementing EU Regulation 2021/2282 on Health Technology Assessment. Drawing on survey data and structured discussions at the 2024 European Access Academy, the authors found that 65.5 % of respondents reported insufficient expert involvement in joint assessments, only 37.9 % anticipated faster national decision-making, and views on conflict-of-interest transparency were mixed. Stakeholders prioritized earlier and broader expert engagement, stronger EMA–EU HTA coordination, and increased national-level support.

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Sustainability Publications Digest. In a recent publication, Friedericy et al. assessed the environmental footprint of inhalation anaesthetics in Dutch hospitals and surveyed anaesthesiologists on practice patterns. A comprehensive 2019 bottom-up evaluation of anaesthetic agent procurement across the Netherlands was conducted. The analysis revealed relatively low greenhouse gas emissions, largely due to the widespread preference for intravenous anaesthesia and the limited use of inhalation-based techniques.

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Publications Digest. In a recent publication, Polmear et al. examined the growing application of Bayesian statistical methods in orthopedic research, highlighting their advantages over traditional P value-based approaches. The authors emphasized how Bayesian analysis can offer more nuanced interpretations in clinical contexts. Through practical examples ‒ such as diagnostic decision-making in prosthetic joint infection and comparative analysis from the orthopedic trial ‒ the review illustrated key Bayesian concepts and offered guidance for critically evaluating such studies.

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its EU HTA Publications Digest. In a recent publication, Goetz et al. examined where EUnetHTA guidance documents require further methodological clarity in light of the upcoming EU HTA regulation. Through a systematic document review and structured stakeholder discussions conducted in Austria, the authors identified 32 key areas in need of refinement ‒ primarily related to evidence synthesis and eligibility criteria. Drawing on established HTA and evidence synthesis handbooks, the authors proposed concrete methodological options, offering actionable insights to support implementation across EU member states.

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Sustainability Publications Digest. In a recent publication, Ali et al. explored practical strategies to reduce the ecological impact of dermatological surgery in the UK, aligning with the National Health Service's commitment to sustainability. The review outlined key system-wide approaches, including reducing overall surgical activity through prevention, promoting research and innovation, and enhancing service management. The authors also highlighted the critical role of managerial policy, procurement practices, and supply chain dynamics in supporting broader national and international sustainability goals.

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Health Economic Publications Digest. In a recent publication, Donovan et al. introduced Cost-IS, a novel tool designed to support the economic evaluation of implementation strategies for digital health solutions. Its development followed a structured, multi-phase approach involving a literature review, expert interviews, and a modified e-Delphi process. A panel of 12 multidisciplinary experts reached a consensus on the instrument’s core design, though additional piloting is required to evaluate its real-world feasibility and generalizability.

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Publications Digest. In a recent publication, Bourke et al. proposed a novel conceptual framework to support Health Technology Assessment (HTA) processes in reflecting the real-world burden on caregivers. Addressing the current gap in HTA practices caused by limited methodological guidance, the authors offer a structured approach to capture caregiving intensity and duration. Their recommendations aim to assist policymakers, researchers, and manufacturers in aligning HTA submissions with a broader societal perspective.

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its EU HTA Publications Digest. In a recent publication, Tanner et al. examined key cross-functional challenges stemming from Joint Scientific Consultations (JSC) and Joint Clinical Assessments (JCA) and how manufacturers should address them in their EU HTAR readiness plans. Conducted through literature review, guidance analysis, and manufacturer insights, the study identified five key cross-functional areas: global asset strategy, non-EU regional readiness, launch sequence evolution, brand perception, and pricing impacts. Given the central role of market access in bringing innovation to patients, the EU HTAR will have far-reaching implications, with early Joint Clinical Assessment reports expected to significantly influence brand strategy, pricing dynamics, and global launch sequencing.

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Sustainability Publications Digest. In a recent publication, Ali et al. explored practical strategies to reduce the carbon footprint of dermatological surgery in the UK, aligning with the National Health Service's commitment to sustainability. The review outlined systemic measures such as sourcing from local suppliers to cut transport-related emissions, implementing streamlined care pathways, and promoting responsible prescribing. It also emphasized the integration of environmental principles into surgical education and the optimization of resource use for consumables, equipment, and energy.

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Health Economic Publications Digest. In a recent publication, Mascarenhas et al. analyzed the landscape of economic evaluations for medical devices in pediatrics, critically appraising their methodological rigor. The systematic literature review identified 39 economic evaluations, with a focus on high-risk therapeutic devices mostly studied in high-income countries. The analysis showed a predominant use of cost-utility analysis and considerable variation in adherence to CHEERS 2022 reporting standards. The findings highlight the need to improve reporting quality and develop methods that reflect the unique health needs of children, including outcome measures meaningful to pediatric patients and their families.