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Publications Digest

16
Jul 2025

Sustainability Publication Digest: Using Chronic Kidney Disease as a Model Framework to Estimate Healthcare-Related Environmental Impact

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Sustainability Publications Digest. In a recent publication, Garcia Sanchez et al. developed a framework to quantify the environmental impacts of a disease care pathway, using chronic kidney disease (CKD) as a model.
15
Jul 2025

Health Economic Publication Digest: A Comprehensive View of the Methods Used to Measure the Societal Impact of Healthcare Interventions: A Systematic Review

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Health Economic Publications Digest. In a recent publication, Seddik et al. systematically reviewed the approaches used to measure the societal impact of healthcare interventions to clarify concepts and establish a comprehensive analytical framework.
08
Jul 2025

Health Economic Publication Digest: Including Productivity as an Element to Reflect Value of the Treatment: A Systematic Review of Published Health Economic Evaluations

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Health Economic Publications Digest. In a recent publication, Mamiya et al. conducted a systematic review to examine how productivity gain or loss is measured in health economic evaluations, aiming to identify the most widely used instruments and their properties.
07
Jul 2025

Publication Digest: Defining Biological and Clinical Plausibility: The DICSA Framework for Protocolized Assessment in Survival Extrapolations Across Therapeutic Areas

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Publications Digest. In a recent publication, Heeg et al. proposed a systematic framework to define biologically and clinically plausible survival extrapolations, addressing inconsistencies in current health technology assessments (HTA).
03
Jul 2025

Sustainability Publication Digest: Potential impacts to human health from climate change: A comparative life-cycle assessment of single-use versus reusable devices flexible ureteroscopes

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Sustainability Publications Digest. In a recent publication, Thöne et al. performed a comparative life-cycle assessment of single-use and reusable flexible ureterorenoscopes to quantify their greenhouse gas emissions and health impacts within a German hospital setting. The study demonstrated that reusable devices are associated with nearly four times fewer greenhouse gas emissions and lower Disability-Adjusted Life Years per intervention than single-use instruments. These findings underscore that medical device choices can have substantial environmental and health impacts, supporting a shift toward more sustainable healthcare solutions.
02
Jul 2025

Health Economic Publication Digest: Development of an instrument (Cost-IS) to estimate costs of implementation strategies for digital health solutions: a modified e-Delphi study

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Health Economic Publications Digest. In a recent publication, Donovan et al. introduced Cost-IS, a tool designed to estimate the costs of implementing digital health solutions. Its development involved a modified e-Delphi process with 12 experts, who reached consensus on its core design and components. However, consensus was lacking regarding the required user knowledge, how specific the tool should be for digital health, and its digital availability. The authors concluded that further testing is needed to establish the tool’s feasibility in real-world settings.
01
Jul 2025

Publication Digest: Health Technology Assessment and Cardiology: A Review of the Present and Future of Innovation

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Publications Digest. In a recent publication, Casado-Arroyo et al. assessed the current landscape of health technology assessment (HTA) for innovative cardiology devices in Europe. The review identified three central themes: the expanding role of clinicians in HTA processes, the integration of digital technologies and AI into assessment frameworks, and significant variation in HTA practices across EU countries. The authors noted that new regulatory initiatives, such as the HTA Regulation, could facilitate alignment between clinical practice, evidence-based evaluation, and reimbursement processes.
25
Jun 2025

Sustainability Publication Digest: Decarbonizing surgical care: a qualitative systematic review guided by the Congruence Model

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Sustainability Publications Digest. In a recent publication, Kloevekorn et al. conducted a qualitative systematic review to analyze direct sources of carbon emissions in hospital surgical care, using the Congruence Model as a framework. The authors found that major emission sources include anesthetic gases, sterilization practices, and ingrained workplace behaviors, while sustainability efforts are primarily linked to waste policies. The study highlights the value of the Congruence Model for uncovering challenges in decarbonizing surgical care.
24
Jun 2025

Publication Digest: Use of Real-World Evidence in Health Technology Reassessments Across 6 Health Technology Assessment Agencies

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Publications Digest. In a recent publication, Jaksa et al. conducted a targeted review of health technology reassessments across six international HTA agencies to examine the use of real-world evidence (RWE). The analysis of 40 recent reassessments found that 55% incorporated RWE, primarily drawing on registry data to address clinical uncertainties. However, RWE use did not alter patient access outcomes, and no de novo comparative RWE studies were identified, highlighting the need for greater alignment between agencies and sponsors on evidence needs and study feasibility.