Coverage with evidence development (CED)

In July 2025, the Dutch Healthcare Institute (ZIN) announced a new policy framework “Reimbursement within Research” (Vergoeding in Onderzoek), which allows temporary reimbursement under basic health insurance during the evaluation period for specialist medical care and medical devices with limited evidence of effectiveness. ZIN is currently reviewing the framework to provide advice on implementation. The launch of the new framework is expected in November 2025.

On July 15, 2025, the Ministry of Labor, Health, Solidarity, and Families published the instruction on the application for coverage with evidence development programs for 2025-2026. The instruction details the specific fields of research, the application procedures, and the deadlines for different types of programs (PHRC, PRME, PREPS, PHRIP, and PRT).

On June 10, 2025, the Swiss Federal Office of Public Health published updates to the Healthcare Benefit Ordinance (KLV/OPre), which determines coverage of medical services in Switzerland. The changes will take effect on July 1, 2025, and relate to colorectal cancer screening with the increase in the number of reimbursed colonoscopies, cancer treatment, men’s health, medical aids, and other medical services.

On November 29, 2024, the Ministry of Health and Access to Care published an Order outlining the requirements for application files to request coverage of innovative biology or pathology procedures within the new RIHN 2.0 framework. The Order concerns the application file model and list of supporting documents for coverage requests

On December 2, 2024, the Swiss Federal Office of Public Health published the changes that will occur to the Healthcare Benefit Ordinance (KLV/OPre), which determines coverage of medical services in Switzerland. The updates will enter into force on January 1, 2025, and they relate to the list of explicitly evaluated services (Annex 1 of KLV/OPre), outpatient-before-hospital services (Annex 1a), List of Tools and Equipment (Annex 2), and the List of Analyses (Annex 3).

At the beginning of October 2024, the Ministry of Labor, Health, and Solidarity published the amounts awarded for the Health Economic Research Program (PRME) projects submitted in 2023 and selected for funding.

In July 2023, the National Institute for Health and Disability Insurance (INAMI-RIZIV) significantly updated the process to obtain reimbursement for health apps. More stakeholders, including the industry, can now submit an application to INAMI-RIZIV for temporary or permanent reimbursement. The new process will come into force on October 1, 2023.

On March 8, 2023, the Ministry of Health and Prevention published an Order in the Official Journal of the French Republic on the coverage of the INTERVAPOR system for lung volume reduction under Forfait innovation program.

Rehabilitation before or after a primary knee or hip replacement using a health app is temporarily reimbursed in Belgium under a specific agreement with the National Institute for Health and Disability Insurance (INAMI-RIZIV). Reimbursement was limited to patients participating in the clinical study. From October 01, 2022, all patients eligible for rehabilitation before and after a primary knee or hip replacement will receive it using a health app in combination with a certain minimum number of classic face-to-face physiotherapy sessions. Certain health apps must be included in the list of reimbursable mobile applications. For now, only one app (MoveUP Coach) is included.

On June 22, 2022, the list of awarded PHRC and PRME projects, submitted in 2021, was published on the website of the French Ministry of Health and Prevention.

On June 22, 2022, the French Ministry of Health and Prevention published the instruction related to the 2022 application for coverage with evidence development programs. In the instruction, the specific fields of research, the application procedures, and the deadlines for applications for different types of projects (PHRC, PRME, PREPS, PHRIP, PRT) are specified.

On July 29, 2021, the French Ministry of Solidarity and Health published the instruction related to the 2021 application for coverage with evidence development programs. In the instruction, the specific fields of research, the application procedures, and the deadlines for applications for different types of projects (PHRC, PRME, PREPS, PRT) are specified.