Publication Digest: Large simple randomized controlled trials-from drugs to medical devices: lessons from recent experience

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Value-based Publications Digest. In a recent publication, Vogler et al. proposed fit-for-purpose policy recommendations based on the analysis of current funding and pricing structures for point-of-care tests (POCTs) for community-acquired acute respiratory tract infections across Europe. The authors aimed to improve antibiotic prescribing for respiratory infections by enhancing the uptake of POCTs. The study suggested several funding policy and pricing-related recommendations ‒ such as physician-focused remuneration models, public reimbursement coverage, and strategic procurement approaches ‒ which can substantially boost the implementation of rapid diagnostic tools in outpatient settings.

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Sustainability Publications Digest. In a recent publication, Haluza et al. conducted an exploratory survey at the General Hospital in Vienna, Austria, to assess anesthesia team members’ perspectives on precycling and recycling of anesthetic gases. The study revealed a generally positive attitude toward adopting sustainable practices, suggesting a strong potential for reducing volatile anesthetic use through active staff engagement.

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Health Economic Publications Digest. In a recent publication, Cocco et al. applied early economic modeling to establish target product profile specifications based on cost-effectiveness considerations, helping developers define key test performance criteria. The authors used the example of a novel rapid diagnostic for Clostridioides difficile infection in the UK setting. The study underscores how well-defined target product profiles can guide diagnostic test development to address pressing clinical needs.

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Value-based Publications Digest. In a recent publication, Messori et al. analyzed an algorithm for identifying innovative, high-risk medical devices in Tuscany, Italy. Due to its limitations ‒ such as a narrow selection of qualifying devices and reliance on strict objective criteria ‒ the authors introduced a "potentially innovative" category to accommodate devices with clinical and economic value. Based on an analysis of 17 devices, this refined classification supports a structured procurement approach, with plans for regional implementation in hospitals in the coming months.

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Sustainability Publications Digest. In a recent publication, Morris et al. conducted a scoping review of data on waste and greenhouse gas emissions in ophthalmic surgery. Results of 10 studies revealed that most emissions are linked to the procurement of surgical materials, followed by travel emissions and building energy. The authors also proposed a standardized waste-lifecycle framework to organize future research to help generate robust evidence for implementing impactful waste reduction strategies in ophthalmology.