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Health economics

09
Apr 2025

Health Economic Publication Digest: Development of an instrument (Cost-IS) to estimate costs of implementation strategies for digital health solutions: a modified e-Delphi study

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Health Economic Publications Digest. In a recent publication, Donovan et al. introduced Cost-IS, a novel tool designed to support the economic evaluation of implementation strategies for digital health solutions. Its development followed a structured, multi-phase approach involving a literature review, expert interviews, and a modified e-Delphi process. A panel of 12 multidisciplinary experts reached a consensus on the instrument’s core design, though additional piloting is required to evaluate its real-world feasibility and generalizability.
02
Apr 2025

Health Economic Publication Digest: Economic evaluations of medical devices in pediatrics: a systematic review and a quality appraisal of the literature

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Health Economic Publications Digest. In a recent publication, Mascarenhas et al. analyzed the landscape of economic evaluations for medical devices in pediatrics, critically appraising their methodological rigor. The systematic literature review identified 39 economic evaluations, with a focus on high-risk therapeutic devices mostly studied in high-income countries. The analysis showed a predominant use of cost-utility analysis and considerable variation in adherence to CHEERS 2022 reporting standards. The findings highlight the need to improve reporting quality and develop methods that reflect the unique health needs of children, including outcome measures meaningful to pediatric patients and their families.
26
Mar 2025

Health Economic Publication Digest: Economic Considerations of Cardiovascular Implantable Electronic Devices for The Treatment of Heart Failure

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Health Economic Publications Digest. In a recent publication, Elsner et al. conducted a literature review to evaluate the economic value of cardiovascular implantable electronic devices for heart failure treatment, with a focus on the European context over the past 10 years. The review assessed the economic implications of various device therapies, including cardiac resynchronization therapy with a pacemaker (CRT-P), CRT with a defibrillator (CRT-D), implantable cardioverter-defibrillators (ICDs), pacemakers, and (semi)automated telemonitoring, using QALYs and ICERs as standardized measures of cost-effectiveness. All cardiovascular implantable electronic devices were found to fall within commonly accepted cost-effectiveness thresholds.
19
Mar 2025

Health Economic Publication Digest: Consolidated Health Economic Evaluation Reporting Standards for Interventions That Use Artificial Intelligence (CHEERS-AI)

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Health Economic Publications Digest. In a recent publication, Elvidge et al. introduced the CHEERS-AI checklist, a standardized reporting framework for economic evaluations of AI-based health interventions. Developed through a Delphi study with multidisciplinary experts, the checklist comprises 38 reporting items, including AI-specific considerations. By improving transparency and reproducibility, CHEERS-AI aims to enhance the quality of cost-effectiveness assessments and facilitate informed decision-making in AI-driven healthcare.
12
Mar 2025

Health Economic Publication Digest: Estimation of the maximum potential cost saving from reducing serious adverse events in hospitalized patients

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Health Economic Publications Digest. In a recent publication, Larsen et al. explored potential healthcare savings in Denmark associated with the use of artificial intelligence-assisted vital signs monitoring systems. Based on the hypothesis, implementing these systems could potentially reduce the occurrence of serious adverse events in hospitalized patients. Utilizing Danish national registry data, the authors estimated economic benefits from the implementation of AI-assisted monitoring systems, highlighting significant potential savings from decreased length of hospital stay and fewer readmissions. However, the study highlighted the need for a more precise evaluation of the clinical effectiveness of AI-assisted technologies and detailed consideration of associated implementation costs.
05
Mar 2025

Health Economic Publication Digest: The Paradigm Shift From Patient to Health Consumer: 20 Years of Value Assessment in Health

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Health Economic Publications Digest. In a recent publication, van den Broek-Altenburg et al. reviewed 20–25 years of economic value assessment approaches in healthcare, highlighting the growing focus on individual preferences over broad societal metrics in value-based care models. The study underscores the complexities of incorporating patient-specific preferences into economic evaluations, and addresses recognized limitations of QALY measures. The authors discussed emerging alternative valuation frameworks that could influence future policy and reimbursement decision-making.
26
Feb 2025

Health Economic Publication Digest: Challenges and recommendations for collecting and quantifying implementation costs in practice: a qualitative interview study

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Health Economic Publications Digest. In a recent publication, Donovan et al. conducted a qualitative interview study with 16 experts to investigate the gaps in capturing implementation costs within economic evaluations. The study revealed four key barriers: difficulties in defining, collecting, and valuing implementation costs; the lack of standardized methodologies; and the lack of multidisciplinary collaboration in enabling implementation costing. The authors advocated for standardized approaches to implementation cost estimation, emphasizing that improved methodologies could enhance confidence in economic assessments and better inform resource allocation.
18
Feb 2025

Health Economic Publication Digest: Early Economic Modeling to Inform a Target Product Profile: A Case Study of a Novel Rapid Test for Clostridioides difficile Infection

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Health Economic Publications Digest. In a recent publication, Cocco et al. applied early economic modeling to establish target product profile specifications based on cost-effectiveness considerations, helping developers define key test performance criteria. The authors used the example of a novel rapid diagnostic for Clostridioides difficile infection in the UK setting. The study underscores how well-defined target product profiles can guide diagnostic test development to address pressing clinical needs.
11
Feb 2025

Health Economic Publication Digest: Economic Evaluations of mHealth Interventions for the Management of Type 2 Diabetes: A Scoping Review

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Health Economic Publications Digest. In a recent publication, Tornvall et al. conducted a systematic review of 12 economic evaluations of mHealth interventions for type 2 diabetes management. Most solutions ‒ featuring smartphone applications with text messaging and connected medical devices ‒ were generally deemed cost-effective or cost-saving. However, the authors highlighted moderate reporting quality, with a median CHEERS score of 59%. Methodological heterogeneity in outcome reporting further limits the overall robustness and comparability of the evidence for decision-makers.
06
Feb 2025

Health Economic Publication Digest: A review of methods for the analysis of diagnostic tests performed in sequence

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Health Economic Publications Digest. In a recent publication, Fanshawe et al. systematically reviewed statistical methods for analyzing the performance of sequential diagnostic testing. The authors addressed five key themes: methods for combining tests, estimation of conditional dependence, repeated testing for risk assessment, adjustment for an imperfect reference standard, and meta-analysis of test sequences. This review offers methodological insights that enhance the precision and reliability of diagnostic evaluations.