Core value dossiers for medical technologies
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White Paper: Challenges and Proposed Solutions in SLR for Medical Devices
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Publication Digest: The AMSTAR 2 publication lacks explicit instructions on how to assess the appropriateness of statistical methods (item 11) and publication bias (item 15) and does not reflect advances in meta-analysis
MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Publications Digest.
In a recent publication, Spineli critically examined limitations of the AMSTAR 2 appraisal tool used to assess the methodological quality of systematic literature reviews. The author focused on statistical methods (item 11) and publication bias (item 15), and proposed refinements to reflect advances in meta-analysis and ensure alignment with the Cochrane Handbook. The commentary concludes that appraisers should consult with meta-analysts and rely on up-to-date methodological guidance when evaluating statistical approaches in systematic reviews.
Access the full-text article here.