On March 4, 2021, INAMI-RIZIV announced the development of a multi-year trajectory for the health care budget in which will define the allocation of resources for health care objectives for 2022-2024.

Starting April 2021, a significant change of the payment system for specialist care is expected in England. Most of the activity-based funding will be replaced by a blended payment model, including a fixed payment component and a variable component. All agreements will be made locally between commissioners and providers. This will be the next step towards abolishing activity-based (HRG-based) reimbursement according to the NHS Long-Term Plan.

The Dutch Healthcare Institute (ZIN), in collaboration with the Ministry of Health, Welfare and Sport (VWS), Dutch Health Authority (NZa), and Health and Youth Care Inspectorate (IGJ), implemented an extension of existing digital healthcare innovation programs called "ZorgZandbak" to demonstrate how digital care could become an integral part of regular care.

On February 18, 2021, the updated List of Reimbursable Products and Services (LPPR) was published. It contains new devices included in the LPPR list in January-February 2021, as well as other modifications made during this period. The newly-included devices belong to the cardiovascular (TAVI), ENT (cochlear and brainstem implants), and diagnostic imaging (FFR) technology groups.

In late February 2021, the Delen collaboration platform of NHS Digital issued 2021 National Clinical Coding Standards (NCCS) OPCS-4.9 and ICD-10 reference books that must be used during the procedure and diagnosis coding from April 01, 2021. The updates mainly concerned endoscopic procedures, transarterial chemoembolization (TACE) of the liver, peripheral vascular procedures using stents and stent-grafts, gynecological procedures using meshes, and bone densitometry.

In March 2021, the new mini-HTAs of five technologies were initiated in Norway: Harpoon - transapical neochordae device, tricuspidal clip, portable hand-held spirometry, CGM device and insulin pump, and portable spirometry device. The final mini-method assessment will be published in the National Database for Mini-HTA.

On February 23, 2021, NHSX launched Digital Technology Assessment Criteria for health and social care (DTAC), the new national criteria designed to provide suppliers and healthcare organizations a clear direction on building and buying good digital health technologies. DTAC will apply to all types of digital health technologies, from public-facing health apps to digital systems used within hospitals. The assessment criteria are focused on five areas: digital technologies will receive a pass or fail in four categories - clinical safety, data protection, technical security and interoperability, and a score on usability and accessibility.

On March 1, 2021, the Technical Agency for Information on Hospitalizations (ATIH) published the preliminary version of the French DRG manual for 2021.

In the middle of February 2021, the Swedish Dental and Pharmaceutical Benefits Agency (TLV) launched the assessment on the following prognostic platforms for gene diagnostics in breast cancer: Oncotype DX, MammaPrint, ProSigna. The evaluation is planned for the spring of 2021.

On February 24, 2021, NHS England published an update of the Specialized Services Policy Pipeline (covering period November 10, 2020 - February 10, 2021). Two new Clinical Commissioning Policies were added to the work program, and seven new policies were published, including stereotactic ablative radiotherapy, stereotactic radiosurgery and proton therapy. The status of ongoing policies was updated as well.

In late February 2021, eleven out of fifteen needed members and three observers of the Treatment Council (Behandlingsråd) were appointed in Denmark. The Treatment Council is a new model for assessing treatment methods and health technologies, expected to become fully operational in early 2021. Earlier in February 2021, the final method and process framework of the Treatment Council was approved.

In February 2021, the National Institute for Health and Care Excellence (NICE) published one new medical technologies guidance (Leukomed Sorbact for preventing surgical site infection) and seven new Medtech innovation briefings (PROPEL sinus implants, URO17 for detecting bladder cancer, Faecal microbiota transplant, DOAC Dipstick for detecting oral anticoagulants, CytoSorb for reducing the risk of bleeding during cardiac surgery, and others).