In September 2019, the Andalusian Health Technology Assessment Department (AETSA) has released an assessment report regarding the evaluation of PET scan usefulness in non-oncological indications. The performed analysis showed that the quality of available systematic reviews related to the issue is generally low and, in some cases, moderate. The high-quality reviews, which conclude that routine use cannot be recommended, were found only for the indication of cognitive impairment with suspected Alzheimer's disease.