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September 2025 Med Tech-related health technology assessments from the NIHR in England
The National Institute for Health and Care Research (NIHR) funds valuable independent research for health and social care decision-makers in England. Reports from the Health Technology Assessment (HTA) Programme are published in the NIHR HTA Journal and inform the National Institute for Health and Care Excellence (NICE) guidance.
In September 2025, four Med Tech-related assessments were published in the NIHR HTA Journal. The examples of evaluations are provided below:
- Perioperative oxygen therapy in patients undergoing surgical procedures based on an overview of systematic reviews and meta-analyses. The study's objective was to provide an overview of the effectiveness of perioperative oxygen therapy and formulate recommendations to inform clinical decision-making and research. It was concluded that there is no clear evidence that either a high or a low fraction of inspired oxygen improves outcomes in surgical patients. Existing evidence is insufficient for recommending routine use of non-invasive ventilation or high-flow nasal oxygen;
- The assessment of diagnostic strategies for suspected acute aortic syndrome based on systematic review, meta-analysis, decision-analytic modelling, and value-of-information analysis. The study's objective was to estimate the accuracy of clinical scores and biomarkers for diagnosing acute aortic syndrome, the cost-effectiveness of alternative diagnostic strategies, and the expected value of future research. Diagnostic strategies included the Aortic Dissection Detection Risk Score and D-dimer to select patients for computed tomographic angiography. It was concluded that the Aortic Dissection Detection Risk Score and D-dimer provide valuable diagnostic information and may offer cost-effective strategies for selecting patients for computed tomographic angiography. Still, their role depends upon how clinicians identify suspected acute aortic syndrome.
Other assessments published in September 2025 concerned the effectiveness of surgical interventions in patients with severe pressure ulcers and quantitative fecal immunochemical tests to guide colorectal cancer pathway referral in primary care.
See the full details here.
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