Publication Digest: Heterogeneity in meta-analyses: an unavoidable challenge worth exploring

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Publications Digest. 

In a recent publication, Choi et al. explored the concept of heterogeneity in meta-analyses, aiming to review the main sources of heterogeneity between studies and how it shapes pooled estimates. The authors synthesized established statistical tools and practical strategies to better detect, interpret, and manage heterogeneity. Their findings underscored that embracing heterogeneity strengthens the robustness of pooled evidence and enhances the credibility and clinical relevance of meta-analytic conclusions. 

Access the full-text article here.