Publication Digest: A Systematic Literature Review of Important and Meaningful Differences in the EQ-5D Index and Visual Analog Scale Scores

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its EU HTA Publications Digest. In a recent publication, Sarri et al. investigated the methodological alignment between EU joint clinical assessments and national HTA requirements in France, Germany, The Netherlands, and Spain. While the study found strong consensus on the need for systematic evidence generation, national agencies diverged in their guidance on evidence derived from indirect treatment comparisons. These findings highlight the challenges health technology developers face in meeting both EU-wide and local evidentiary demands.

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Sustainability Publications Digest. In a recent publication, Garin et al. developed a framework to promote sustainable inhaler prescriptions in Spain. The authors created a national database and decision-making algorithm to integrate environmental impact into clinical decision-making processes. Their analysis found that targeted shifts from high-emission pressurized metered-dose inhalers to dry powder inhalers could yield substantial environmental benefits. The study offers actionable insights for aligning respiratory treatment practice with environmental sustainability.

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Publications Digest. In a recent publication, Weimar et al. developed a taxonomy and identified six archetypes of business models used by digital health technologies (DHTs) in the European Union. Drawing from 169 real-world DHT cases and 13 expert interviews, the study categorized models as: (1) administration and communication supporter, (2) insurer-to-consumer digital therapeutics and care, (3) diagnostic and treatment enabler, (4) professional monitoring platforms, (5) clinical research and solution accelerators, and (6) direct-to-consumer wellness and lifestyle. The authors identified three key innovation drivers in the DHT commercialization landscape: the direct targeting of patients and private individuals, the use of artificial intelligence as an enabler, and the development of DHT-specific reimbursement pathways.

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its EU HTA Publications Digest. In a recent publication, Julian et al. investigated how EU stakeholders perceive key challenges in implementing EU Regulation 2021/2282 on Health Technology Assessment. Drawing on survey data and structured discussions at the 2024 European Access Academy, the authors found that 65.5 % of respondents reported insufficient expert involvement in joint assessments, only 37.9 % anticipated faster national decision-making, and views on conflict-of-interest transparency were mixed. Stakeholders prioritized earlier and broader expert engagement, stronger EMA–EU HTA coordination, and increased national-level support.

MTRC shares the most relevant and impactful publications in the field of market access and HEOR for medical technologies in Europe through its Sustainability Publications Digest. In a recent publication, Friedericy et al. assessed the environmental footprint of inhalation anaesthetics in Dutch hospitals and surveyed anaesthesiologists on practice patterns. A comprehensive 2019 bottom-up evaluation of anaesthetic agent procurement across the Netherlands was conducted. The analysis revealed relatively low greenhouse gas emissions, largely due to the widespread preference for intravenous anaesthesia and the limited use of inhalation-based techniques.