On September 16, 2021, the Federal Joint Committee (G-BA) has decided that it would not evaluate the proton therapy in a number of indications, including esophageal cancer and inoperable hepatocellular carcinoma (HCC).

In October 2021, the National Board of Health and Welfare released the Swedish version of the 2022 NordDRG. Six new DRGs were added, and they concern the cardiovascular area, vaccination, cochlear implants, and visits in primary care. Also, several changes in DRG content and logic were made.

In October 2021, NHS England issued an updated version of the National Genomic Test Directory for 2021/2022, which lists genomic tests commissioned by NHS England via Genomic Laboratory Hubs. Twenty new codes (test-indication combinations) were introduced in the cancer field, and 115 new codes were added for rare and inherited diseases.

The revised EBM (German Uniform Evaluation Standard) catalog came into force on October 1, 2021. The most significant changes concern mainly IVD tests: extension of the newborn screening, the introduction of microsatellite instability testing, amendments of Oncotype DX® test reimbursement, the introduction of screening for hepatitis B and C as part of health check-up, as well as changes in reimbursement of radiation therapy services.

On September 27, 2021, the Decision Forum for "New Methods" decided not to introduce bronchial thermoplasty as a routine treatment of patients with severe asthma. The method should only be used within clinical trials.

On September 23, 2021, NHS England and NHS Improvement (NHSE/I) published the National bundle of care for children and young people with asthma, which is phase one of a plan to support Integrated Care Systems (ICSs) in delivering high-quality asthma care.

On September 15, 2021, the Evaluation Committee (Bewertungsausschuss) has decided to introduce in the EBM (German Uniform Evaluation Standard) the new code for Oncotype DX® testing. This change is introduced in the updated EBM version, which was published on October 1, 2021.

On September 23, 2021, the Norwegian Directorate of e-Health released an updated version of the National Laboratory code (NLK) system and associated tariffs for state and private laboratories to be implemented no later than November 01, 2021. NLK system has been used for activity-based reimbursement by the Norwegian Health Economics Administration (Helfo) in outpatient settings since 2018. Thirty-nine new codes were added in medical biochemistry, clinical pharmacology, and medical microbiology areas.

On September 29, 2021, NHSX announced the first phase winners of a Digital Health Partnership Award aimed to help NHS organizations receive funding to accelerate the adoption of digital health products and services to monitor patients with long-term conditions remotely. There will be three categories of funding: projects requiring the support of up to £100,000, £250,000, and £500,000.

In September 2021, the Norwegian Directorate for e-Health released the procedure coding system for 2022. A total of 75 new codes were introduced: eight new surgical procedure codes concerning gastroenterology, men's health, obstetrics and gynecology, cardiovascular and surgical procedures, 53 new radiology procedure codes, and 14 new medical procedure codes.

In September 2021, the National Institute for Health Research (NIHR) in England released two MedTech-related reports in its Health Technology Assessment (HTA) Journal, which concerned non-invasive imaging software for coronary stenosis assessment (QAngio XA 3D/QFR and CAAS vFFR) and quantitative fetal fibronectin test to predict preterm labor. HTA Journal publishes research reports on the effectiveness, costs, and broader impact of health technologies for those who use, manage, and provide care in the NHS and informs National Institute for Health and Care Excellence (NICE) guidance.

In late September 2021, the Danish Health Authority (Sundhedsdatastyrelsen) has opened the application period for submitting proposals for new national screening programs in 2022. The deadline for the submission of the applications is December 1, 2021.